Unexpected side-effect: how common medications clear the way for pathogens

Study led by the University of Tübingen: many non-antibiotics weaken the natural protective function of the intestine – with consequences for the colonization with pathogenic bacteria.

Further information

Scientific contact:

Prof. Dr. Lisa Maier
University of Tübingen
Interfaculty Institute for Microbiology and Infection Medicine (IMIT)
Cluster of Excellence ‘Controlling Microbes to Fight Infections’ (CMFI)
M3 Research Center
Phone +49 7071 29-82536
l.maier@uni-tuebingen.de
Maier Lab website

Dr. Anne Grießhammer
University of Tübingen
Interfaculty Institute for Microbiology and Infection Medicine (IMIT)
Cluster of Excellence ‘Controlling Microbes to Fight Infections’ (CMFI)
anne.griesshammer@med.uni.tuebingen.de

Dr. Jacobo de la Cuesta-Zuluaga
University of Tübingen
Interfaculty Institute for Microbiology and Infection Medicine (IMIT)
Cluster of Excellence ‘Controlling Microbes to Fight Infections’ (CMFI)
M3 Research Center
Jacobo.delaCuesta@med.uni-tuebingen.de

Press contact:

Leon Kokkoliadis
Public Relations Management
University of Tübingen
Interfaculty Institute for Microbiology and Infection Medicine (IMIT)
Cluster of Excellence CMFI
Phone +49 7071 29-74707 / +49 152 346 79 269
leon.kokkoliadis@uni-tuebingen.de
CMFI website

Publication:
Grießhammer A, de la Cuesta-Zuluaga J, Müller P, Gekeler C, Homolak Jan, Chang H, Schmitt K, Planker C, Schmidtchen V, Gallage S, Bohn E, Nguyen TH, Hetzer J, Heikenwälder M, Huang KC, Zahir T, Lisa Maier. (2025) Non-antibiotic drugs disrupt colonization resistance against pathogenic Gammaproteobacteria. Nature 643. doi: 10.1038/s41586-025-09217-2 (Online-Publikation erfolgte vor der Print-Publikation).
Source:
https://uni-tuebingen.de/en/university/news-and-publications/press-releases/press-releases/article/unexpected-side-effect-how-common-medications-clear-the-way-for-pathogens/