In intensive care medicine, obtaining reliable information quickly is vital in life-threatening situations such as sepsis. The top priority is to be able to speedily administer the right, targeted antibiotic. In the absence of rapid diagnosis and appropriate treatment to prevent imminent organ failure, 70,000 of the 300,000 or so cases of sepsis each year in Germany prove fatal. Consequently, it has long been one of the main causes of death in intensive care units. The latest studies show that serious cases of Covid-19 can also lead to sepsis.
The approach to date has been to create cultures from blood samples. These normally have to be "incubated" for up to five days. Even then, the bacterial pathogen is only determined accurately around 30 percent of the time. In the case of other infections - caused, for example, by the Candida fungus, which attacks the mucous membranes - this process can take up to three weeks. With the diagnostic method developed by Noscendo GmbH, the result is available within 24 hours, including precise details as to which bacterium, DNA virus or fungus is causing the problem. This means, for instance, that instead of broad-spectrum antibiotics, an antibiotic or antimycotic tailored to the pathogen can then be administered. In addition to minimising the side-effects, this also allows the patient to be released far sooner. The method thus relieves the considerable strain on the healthcare system, which isn't limited to the current coronavirus crisis.