Currently, we are looking for a

PhD Student (m/f/d)

Prof. Dr. M. Torzewski's research focuses on the pathogenesis of both atherosclerosis and aortic valve stenosis. Both diseases are characterized by an active remodeling process accompanied by tissue calcification. A number of different cell and molecular biology techniques are used to identify the clinical and physiological relevance of potential triggers of cardiovascular calcification.

Job Description

• Application of a broad spectrum of basic molecular and cell biology techniques, including immunohistochemistry, immunofluorescence,  immunoblotting, and real-time PCR
• Cell culture: Isolation and culture of valve interstitial cells (VICs)/myofibroblasts
• Functional testing of compounds (e.g., lipoprotein modifications, pro- and anti-inflammatory cytokines) in in vitro cell models
• Ex vivo tissue analysis of stenotic aortic valves (histochemical and immunohistochemical analysis)
• Analysis of experimental datasets (e.g., immunohistochemistry, gene expression) using biostatistics and bioinformatics

Qualifications

• Master degree (M.Sc.) in biology, biochemistry, molecular medicine, pharmaceutical sciences, or a related discipline
• Experience and solid background in molecular biology and cell culture technology
• Preliminary practical experience in working with cell culture would be beneficial
• Interest in studying the biology of vascular calcification
• Excellent English written and oral communication skills

Additional Information

• The opportunity to work in an interactive team providing support and mentoring
• State-of-the-art equipment and technologies for a wide range of different applications (e.g. transcriptomics, metabolomics) and expert knowledge within the different core facilities at the institute
• Participation in the PhD program
• The opportunity to communicate scientific results at conferences and to participate in workshops
• Company health management and fitness offers
• Employee discounts at a variety of companies