PhD student (f/m/d) in T cell engineering/ cancer immunotherapy

The Cluster of Excellence EXC2180 “Image-Guided and Functionally Instructed Tumor Therapies (iFIT)” is a multidisciplinary and interdisciplinary research program that focuses on understanding tumor biology and the development of novel diagnostic and therapeutic approaches for cancer. The iFIT research group of Dr. Judith Feucht offers a position for a

 

PhD student (f/m/d) in T cell engineering/ cancer immunotherapy.

The earliest possible start date is December 2020 and the 65%-part-time position is offered for 1 year with plans for a further extension.

The laboratory of Dr. Judith Feucht focuses on enhancing and extending immunotherapeutic approaches with Chimeric Antigen Receptors (CARs) - synthetic receptors that reprogram immune cells for therapeutic purposes. CD19 CAR T cells have yielded remarkable clinical responses in patients with refractory B cell malignancies. Despite the clinical success, treatment with currently approved CAR designs is curative only in a fraction of patients. We aim to use innovative engineering tools and clinically relevant mouse models of solid tumors to gain increased understanding into CAR biology and underlying mechanisms of therapeutic failures. The goal is to develop enhanced CAR designs and combinatorial treatment strategies to improve CAR therapy and to extend its application to a broader range of disease.

Responsibilities:

  • Planning, implementing and performing research experiments
  • Analysis, interpretation and presentation of research findings
  • Contribution to grant writing, research reports and publications
  • Scientific literature research and development of new ideas

Requirements:

  • Diploma or Master’s Degree (or equivalent) in biology, life sciences or related discipline
  • Practical experience in cell culture techniques, immunological assays and/or molecular biology methods
  • Excellent organization, communication and documentation skills
  • Proficiency in English (oral and written)
  • Strong interest in T-cell based immunotherapies and translational research; high level of selfmotivation
  • Creativity and thinking outside the box are encouraged
  • Collegiality and ability to work both independently and as part of a team
  • Practical skills in animal experimentation (FELASA B or comparable) are desirable

We offer an interesting and versatile workplace, a pleasant working atmosphere and a project in a highly innovative and relevant research field. Salary is paid in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States) in addition to all the customary benefits granted to employees working in Public Services. Severely handicapped persons with equal qualifications are given preferential consideration. The University of Tübingen is committed to increase
the percentage of female scientists and therefore encourages women to apply for this position. The Administration of the University Hospital is responsible for all employment matters. Personnel appointments will be made pursuant to the fundamental stipulations of the legal statutes for universities in Germany. Interview expenses are not covered.

Please send your application including a brief cover letter, your CV as well as contact details for two references via e-mail or in written form until 11/15/2020 to:

Dr. med. Judith Feucht
Cluster of Excellence EXC2180 "iFIT"
Otfried-Müller-Str. 14
72076 Tübingen, Germany
Email: Judith.feucht@med.uni-tuebingen.de