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Proteomics

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Involved OrganisationTypeFurther fields of acitivityFocusbased inManagementwas foundet inAddressEmailHomepageProfileContactNumber of employeesBioChancePlusBioProfile
M-fold Biotech GmbHBiotechServices, DevelopmentStructural analyses, in vitro bonding and functional testing of membrane proteins, production of antibodiesTübingenDr. Hans Kiefer, Scientific Director
Dr. Wolfgang Vogt, Managing Director
1999Vor dem Kreuzberg 17
72070 Tübingen
Germany
Tel.: +49 (0)7071-7945-0
Fax: +49 (0)7071-7945-11
contact@m-phasys.comwww.m-phasys.comM-fold Biotech was founded in 1999 as m-phasys by Dr. Hans Kiefer, Dr. Wolfgang Vogt, Marc Lohrmann and i.con. innovation GmbH.

Membrane proteins are the most commercially-interesting target proteins for medications and represent M-fold Biotech GmbH’s core area of expertise yet they are also the most difficult to work with. The key to the firm’s success was the use of the patented M-FOLD technology, which was used to manufacture membrane protein antigens. Using two very different methods (immunisation and “phage display” selection), the firm succeeded in manufacturing antibodies with the required binding properties and biological activity and selectivity.

In addition to structural analysis, m-phasys has recently established a new area of business, namely the manufacture of antibodies that act against membrane proteins and can themselves act as medications.

M-fold Biotech's customers include major pharmaceutical companies who commission the structural analyses in order to develop medications. 		12Structural explanations of therapeutically-relevant potassium channelsAssociated project: Joint project into the generation of antibodies against frizzled receptors (GPCRs) for the isolation and characterisation of stem cells.
gelcompany GmbHBiotechLaboratory TechniquesSystems, gels, fluorescent dyes, buffers for horizontal and vertical gel electrophoresis and analysisTübingenJames Walker
Dipl. Ing. Wolfgang Gstrein
Dr. Hanspeter Schickle
Günter Thesseling
1991Paul-Ehrlich-Str. 15
72076 Tübingen
Tel.: +49 (0)7071-257030
Fax: +49 (0)7071-2570369
www.gelcompany.comgelcompany GmbH, known as ETC Elektrophorese-Technik GmbH up to 2008, has been producing ready-made gels for electrophoresis applications in protein, DNA and RNA analytics for around 20 years. The gels are bonded to a non-fluorescent plastic film and are easy to handle. The specific composition of the carrier film enables the sensitive and specific detection of proteins and nucleic acids with fluorescent dyes. The Australian company Fluorotechnics Pty Limited, which developed a highly sensitive fluorescent dye and an appropriate detection system and markets these throughout the world, realised the potential of the company’s products and acquired ETC GmbH in October 2007. The additional acquisition of San Francisco-based Gel Company, which led to the new company name, enabled Fluorotechnics to broaden its existing product portfolio in October 2008.Günter Thesseling (guenter.thesseling@gelcompany.com)
SensScreen Technologies GmbHBiotechDevelopment, Laboratory TechniquesDevelopment and production of magnetic particles for highly sensitive bioseparationStuttgartDr. Jochen F. Peter (Managing Director)2009Silberburgstrasse 144
D-70176 Stuttgart
Mobil: +49 (0) 173-7069734
jochen.peter@sensscreen.comwww.sensscreen.comSensScreen Technologies GmbH develops and produces magnetic nano- and microparticles as well as new methods for the highly sensitive bioseparation of peptides and proteins from the secretome of cultivated cells or human fluids.
SensScreen Technologies has developed an award-winning technology platform that enables the quick and gentle isolation of highly pure proteins from cell culture supernatants for example. Another major focus is the ultrasensitive detection of secreted peptides and proteins for the optimisation of cell culture methods.
The technology can be used in research carried out at universities, research institutes and companies as well as in the industrial production of proteins and peptides.